College of Medicine, Charles R. MSMW reported more than three times as many total and unprotected sex acts with each primary as they did with each non-primary female partner. Implications for HIV risk and prevention are discussed. Research on MSMWs practices is critical to better addressing the complex interplay of relationship dynamics, sexual behavior, and gender-related factors influencing HIV risk in Black communities. These data are consistent with the possibility that more HIV-positive women could have been infected through sex with MSMW, in addition to those infected through sex with men who have other risk factors. We also note that men who have both male and female partners may be at elevated risk of acquiring STIs, such as gonorrhea and chlamydia, that are more common among women than men [ 2 , 17 ], at least when measured from genital samples.